WTH, I have done tones of research on MTHFR and read a lot of the forums, particularly in the UK there are extensive threads just on this topic. From what I have read there is an indication that even though homocysteine levels don't register as elevated, there is still a link to increased clotting. A lot are saying that even though they did not have high levels, they still benefited from aspirin. My FS has recommended low dose aspirin, and Clexane from ET, though I am in a different situation from you in never having conceived.
CP, it is great you are trying to get answers. I am really interested in the FSH dose for down reg, versus antagonist, versus flare, and agree with Dr S re revisiting your FSH dose. I will need to do some more research, but from what I have always heard, antagonist and flare cycles are better for poor responders, but the contradictory idea is that antagonist cycles will give less follies but better quality, so not quite sure what is going on. Last cycle my FS put me on a lower dose FSH for the antagonist cycle compared to down reg, assuming because I wasn't down regulated I would respond better, but it was the opposite. I spoke with a friend yesterday who is having EPU today on her first antagonist cycle. She had done down reg in the past, hyperstimed on FSH 150, but reponded perfectly on FSH 150 for this antagonist cycle. So by that rational you should up your dose slightly on antagonist to get slightly less follies and ensure no hyperstim.
Does this makes sense? I can't find any info on FSH dose for down reg versus antagonist cycle. Any ideas?
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