A bit late to this thread I guess, but I am in this exact situation right now. I had my nuchal translucency scan earlier this week and it has come back 1 in 60 chance of Downs, 1 in 258 for other trisomy conditions.

I am going straight to amnio because although according to my dates I was only 12w 3d at the time of the scan, the baby was measuring 13w 2d so they are treating me as being already 13 weeks which I am very confused about because this is impossible...I know my dates are accurate - I even had a dating scan at 6 weeks which confirmed it. But this means I can't have a CVS, I have to have an amnio, which I know is lower risk, but it means I have to wait another couple of weeks.

My amnio is being performed at between 14 and 16 weeks which was earlier than I expected...when the OB told me all I could think of was that I was going to have to wait another 6 to 8 weeks.

The doctor performing the procedure has sent me some literature stating that in actual fact their miscarriage rate is far lower than the 1 in 200 (or 1 in 100 for CVS) and it also includes miscarriages that would have happened anyway. This gives me some reassurance but I am very scared that I will miscarry a perfectly healthy baby.

However, a chromosomal disorder is a dealbreaker for both DH and I for various thoroughly considered reasons, not least because I have first hand knowledge of what it is to care for a special needs person, so there was no question that we would go ahead with the test. I will be putting myself on bedrest for the next couple of days following the procedure, even though that isn't really necessary. And I am just trying to think positive in the meantime...after all, there is a far higher chance that this is a false alarm.

But I'd be lying if I said I had slept well since the scan, and I think I have had a permanent headache since then too. Trying very hard to be matter of fact but the tears come when I least expect it.

Good luck.