A Town like Alice (Neville Shute) is an all time favourite - haven't read it in years though, I wonder if I'd be disappointed.

Plus the best one I've read recently is the Timetraveller's Wife.

I love anything by Jodie Piccoult too.

Oh, and anything by Ann Tyler. I love her but her books are hard to get. Good book shops have some in the literature section. If you've never read Ann Tyler, give it a try. Digging to America is a recentish one of hers that I enjoyed.