I would say go for it - and look at joining him for stretches of time. DH works abroad a lot, he's often in different time zones so sometimes we get one day of a weekend together in 3 weeks with minimal phone calls. I quite enjoy this as I get to treat DS to film nights in my bed without worrying about DH needing to sleep in it later.

As for your depression - that's a very real consideration. Is there anyone around you that you could call on in a time of need? Or to set up regular playdates so you had adult company? I know when DH is away I can get Liebling to do more stuff around the house (such as putting his clothes in the laundry basket) because he doesn't see DH not doing it. DS also likes to help load the dishwasher etc so is quite a helpful boy when DH is away.

If I didn't work, I would be spending a bit more time travelling with DH and doing touristy things while he worked (or even taking DS to a local park). As DH works in the same 3 towns a lot, we'd get to meet local people and maybe DS could improve his languages (I know I would!).