OK, I've been thinking about you alot re this situation and I think you should go for the TTC now, because I think it's the only way you are going to be truly happy. With the weight, I was about 15kg overweight when we were tossing up for #4 and DH wanted me to loose at least half of it first, but I said I didn't want to go to all that effort and hard work to loose it when I would put it on again with pg, and I'm someone who does tend to put on a lot of weight with pg, and I also didn't want to put my body under the stress that dramatic changes in weight can do to you kwim? Plus I didn't want to do it, then have to do it all again afterwards. So we struck a deal that we would TTC, but I would try to maintain a healthy weight gain during pg (and I did - I only put on about 15kg which is fabulous for me) and deal with the serious weight loss afterwards (still fighting that battle though ROFL).

As for the MTX and the p, I would take that chance that you will go into some degree of remission while you are pg and after the pg, if you've had some remission it should be a lot easier for the MTX to work and it may work quicker. Plus you know that you cannot fall pg under ANY circumstance while on the MTX (for those that don't know falling pg while on MTX will cause birth defects, not might, but will - it's a multi-purpose drug that is also used for chemotherapy in some cancers) and if that ever happened it would break your heart to have to terminate kwim?

I think your heart wins hands down this time hun