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Thread: IVF with PGD #4

  1. #109

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    Quick post from me...

    CP - I can completely understand where you are coming from - that you kind of want something to be wrong so you can say "ah ha", let's address that and then it will work. I really hope that Dr S can help you figure this out. He sounds amazing from what I've read.

    melbel - good luck with this cycle. I just looked at my notes from my first meeting with a naturopath - she recommended that book as well - but I haven't had time to do anything about it yet. My notes ay "Is My Body Baby Friendly" by Alan Beer.

    AFM - another trisomy! that was the reason for this m/c. So I've had a 2 different spontaneous trisomies. If I get enough embryos from this new method I am going to seriously consider PGD. I just can't go through another messy m/c situation - it's too hard mentally & physically (for me). Nor do I have the time to spare while my body recovers.



    One more week, then we are away...working from home this morning so I can get some laundry done - ridiculous.

  2. #110

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    Buliej - it is good that you found the reason behind your recent MC. Like you, I had two confirmed spontaneous trisomies (most likely declining egg quality), which is why I turned to PGD. And also like you, I commenced DHEA in the hope of raising egg numbers for the IVF/PGD process. Wishing you all the best from here, hun

    Sara, Cuddlepie, WLAB and Kel

  3. #111

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    Hi girls,

    Very quiet in here.

    CPie: Has AF shown up? Wishing you with this cycle.

    WLAB: Keeping fingers crossed for IUI - where are you up to?

    Buliej: Hope you have a great break and please don't think about the Safety Net.

    Kel: Thinking of you, how are you going?

    WTH: Hope you are well again.

    Meredith: Thinking of you.

    AFM - very upset about Safety Net but really relieved that the changes only come into effect on 1 Jan 2009 - have discussed it with DP this morning and I will take that as the deadline to stop trying with my own eggs. We have an appointment with Dr Lok on Tuesday for a second opinion, then awaiting AF at the end of that week and will test FSH. At the moment trying to be very healthy and doing hard bushwalks every weekend.

    Sara

  4. #112

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    A little update for me, well, result for NK cell came back positive, very high actually. The range that Dr.S would like to be 12-18, mine is 30%. So I am a bit upset and scared and hard to get my FS, AF arrived today, seems my cycle for this month is off.

    If you are interested, here is the thread I posted about it:
    http://bellybelly.com.au/forums/long...very-high.html

    sorry no personals today....

  5. #113

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    CP - I'm so sorry that you have to deal with another issue...but is there a bright side to this (as much as there can be)? - meaning now that you know what the issue is, you can address this and hopefully use your frostie (I do hope I'm remembering the facts) to get a sticky bub! Well, I just read your thread and I do see that you have a number of decisions to make and that there are some uncertainties...I am so, so sorry . I hope that the other girls who have had positive NK test results can offer you guidance...and we are all here to support you. As an aside, I finally got the treatment plan for my next cycle - and it involves Prednisolne (the steriod) - 25mg for 5 nights commencing day after trigger - so it does seem that some FS are incorporating this into their treatment plan for reasons other than NK cells.

  6. #114

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    CPie, Just sending hope you get hold of Dr Lok soon and he can help to clarify things for you. Sorry that things are so hard, it's difficult if everything happpens at the same time.

    Sara

  7. #115

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    Thanks Julie and Sara...I was glad that FS called late last night to put my mind at ease. He said no problem to start this cycle straight away and meanwhile, we can discuss about the treatment plan next Friday. Sounds like its not his first time to treat this and he mentioned the exact drug Dr.S mentioned, so I guess I have to have faith in him.

    The good news is AF arrived yesterday and today had blood test, FSH is 7.1, so I can start on FSH injection tomorrow, dosage is now up to 200iu from 75iu last time. I hope the changes including the treatment of NK cells will make some difference.

    Julie, it is interesting to hear that you are also starting Predisolone, although for a different reason. If you read my other thread, Melbel mentioned this can potentially increase egg quality, so I hope one way or another, the end result for your next cycle will be different. Well, we can compare our side effect after taking it. Fun!

    Sara, hope all the exercise is helping you in every aspect, I have everything crossed for you that you will get a green light.

    to everyone else...

  8. #116

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    Very quiet in here

    CPie; How are you going, thinkint of you, hope the BT are going fine.

    Hope evryone is going alright I am just awaiting AF later this week and meanwhile keep myself occupied with lots of bushwalk and some nice things with DP, we'll go into Shane Warne the Musical tonite. Will also see Dr Lok today.

    Sara

  9. #117

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    It is quite in here...

    Thanks Sara for thinking of me, I am just quietly ploding along and tomorrow will have my 1st u/s....will see...

    Good luck with today hun and let us know how you go...

  10. #118

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    CP: goodluck: for Ultrasound tomorrow hope there is a nice number of follies there

    WLAB: how is IUI going, just wondering at what stage you are?

    Kel: Sorry to hear about your donor changing their mind. Hope you'll soon have success on AED

    BDT: Cyclebuddy - has AF shown for you? I expect it later this week.

    Buliej: hope you're having a relaxing break.

    WTH & Meredith

    AFM Appointment with Dr Lok was a lot of food for thought. He basically thinks that my FS should have triggered earlier and that I lost the four follies which were around 20-22mm. He also suggested to use Pregnyl as the trigger. Then he suggested DP to do another sperm test and to do surgical sperm extraction if the result wasn't good - poor DP is afraid of needles and didn't find it at all reassuring that the needle used would be smaller than the one for EPU - must say that I wouldn't have needed to see the very graphic picture about the EPU either - very glad that I've so far always done this under anaesthetic
    The really good thing was that he is not really concerned about high FSH as long as it's below 20!
    Also he said the other option for us are donor eggs and he doesn't think it's a problem to find a donor.
    In any case at this stage I think I prefer my own FS, asked Dr Lok to email her with his suggestions as I thought they all make sense to me.

    Have a great day,

    Sara

  11. #119

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    Hi Ladies

    CPie ; Gl for your scan tommorow, I hope you have just the right ingredients for your bfp

    Sara; I am happy for you that Dr S, said FSH under 20 is good, and that you hava made a decision to stay with your current fs

    Thanks for thinking of me, I felt completly dissapointed with my current FS, hence the change in procedure, then I had another change, and didn't bother to have the IUI with her either. It's a long story that I would rather not post on the threads, so I DTD naturally after the stims, so we will see what happens. Failing that, I have two new FS appointments schedueled, one tommorow morning, and one next week, depending on the outcome, I will go with either, and insist on the colorado, I have the exact same protocol as BullieJ, as we saw the same fs, for a second opintion, however, I have used the safety net to my advantage, and incuded an inital appointment, with two more FS's before I choose a FS, to give this year, our final shot, at ttc with IVF ...

  12. #120

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    Hi Girls,

    WLAB: That sounds like a bad story with your FS it's all hard enough anyway so gettign disppointed by your FS is really not what you needs. Hope you are happy with one of the two FS you're meeting, it's a good Idea to see two as it gives you a number of different viewpoints and can find someone experienced with the issues you're facing.

    CP: Hope your follies keep developing well and growing nicely - sounds like you're having a really good cylce. Looking forward to catching up on the weekend.

    AFM - Already feeling some cramping so AF seems to be close - really hope she is not coming late on Saturday as I really don't want to go to a BT on Sunday as I have arranged to go up to he mountains with some friends for a 20km bushwalk - really looking forward to it. I'd go easy with the black tea as you don't want to get overstimulated.

    I was talking to the nurse when picking up my meds earlier this week and she said it probably would be okay to come in Monday instead if that happens - has anyone done that before - just don't want to mess up my FSH reading.

    Sara

  13. #121

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    Hi ladies i'm a newbie to this thread i am usually on a TTC after loss thread but was recomended to this one as i have lot's of questions and don't know where to start i will give you a quick rundown of whats going on with me.
    I am 35 and DH is 37 this is our 2nd marriage i have 3 boy's to my ex and DH has 1 daughter to his ex we wanted to have a baby together so after 5 months we were pregnant than at 12 weeks our nuchal scan showed a nuchal fold of 4.8mm so we had a 1 in 2 chance of a chromosone abnormality but a C.V.S came back all clear and we found out we were having a girl they said to have early morphology scan to check growth so at 16 weeks they suspected skeletal dysplasia then at 18 weeks it was major heart abnormalities and polydactyl of the hands and one foot with other suspected things we went to the fetal medicine unit at the R.N.S then westmead hospital fetal cardiologist and had many ultrasounds and an amnio so at 19+ weeks we were told that its some sort of genetic syndrome and she most likely wouldn't survive so we had an induction at 19 weeks 5 days and our beautiful girl was born sleeping the autopsy showed abnormalities from head to toe and we had to wait for the D.N.A results i found out today after a ph call that the genetisist and professor at RNS think they know what it is and that DH and i are carrier's of the same faulty gene we have an appt on the 10th of june to find out what syndrome or disorder she had and find out our options i have been told we have a 1 in 4 chance with each pregnancy and i have considered IVF but DH want's to conceive natrually and do CVS at 11 weeks to test for it i hope i havn't raved on i'm at a loss as to what to do next how exspensive is IVF and the whole process is scarey
    Last edited by ferrals5; July 5th, 2009 at 09:09 PM.

  14. #122

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    Ferrals I am so glad you have visited here. This is a fantastic thread where you will find great support and information from women who totally understand and respect your situation.I have replied to your PM so won't repeat all the info.

    to Sara, Cuddlepie, Julie, WLAB, Lisa and Kel. Sending much your way.

  15. #123

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    Hi Ferrals,

    Welcome to this thread - you've gone through so much. Please take care of yourself

    I also had a husband who didn't want to do IVF and we had a one in two chance of having a faulty gen - unfortunately that is what happened and we had to have a termination at 14 weeks, it was the most horrible thing that ever happened to me. During that time I found much support on A Heartbreaking Choice

    I am now with a new partner and we're doing IVF. I am with SIVF - they can do PGD for a large number of genetic abnormalities, for some info check sivf.com.au

    Sara

  16. #124

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    Sara69-Thank's hubby and i spoke about pgd last night and he said if we could afford it we would give it a go but i was told today that the genetisist has sent off tissue samples as they suspect PALLISTER HALL SYNDROME or SMITH LEMLI OPITZ SYNDROME or somthing similar and they can't detect those through pgd only in CVS or AMNIO as they need to find an enzym which is not possible in pgd but they first have to isolate the gene anyway i will keep you up to date cross fingers it's pallister hall syndrome as that one doesn't have to be carried by the parent's it can be a one off mutation.

  17. #125

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    Very quiet in here .....

    Ferral So sorry to hear that things are so complicated, thinkignof you and hoping your find the answer you need.

    CPie: Keeping fingers crossed for trigger tomorrow, look after yoruself, don't go to work if you're not 100% better.

    WLAB: How are you - glad you found a new FS you like - when will you start your next cycle?

    BDT: Cyclebuddy ! How are things did you already have your first BT - hope the new dosage does the trick for you.

    Buliej: Hope you have a relaxing holiday.

    Kel: Not sure if you're still lurking in here you know I am 100% behind you.

    Meredith & WTH

    AFM: I can start! FSH today came back as 10.3, it's probably not great in the greater scheme but was a huge relieve for me - already was preparing myself for bad news like FSH of 20 or higher. The main thing is I can start this cycle - will start jabbing tomorrow night, Puregon dosage of 350. This cycle I am doing the lot to prepare myself mentally, will go to a GP who does acupunture for anxiety, it's bulk billed so will try to do that weekly, also going to my specialist acupunturist in Rozelle at least once a week and more during EPU and the stressful days thereafter, will also talk to the counsellor weekly and going to meditation classes. While the big 4 Birthday is coming up I am taking it easy - tomorrow night it's a dinner with friends and on Sunday a lunch with another group of friends, then next week just a dinner with DP the night before my birthday and going to the theatre with a group fof friends on the night.

    Will just try to enjoy the celebrations and be as relaxed as possible during this cycle - who am I kidding?

    Have a great week,

    Sara

  18. #126

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    Sara- Really happy for you that you can start and a fsh of 10.3 is nothing to be sneezed at. It sounds like you are doing everything humanly possible to relax and give this cycle the best. Wishing you the best.

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