Sushee, I'm pretty sure that's what stopped the synarel working for me first time round. I'm always prone to sinus problems, and the synarel made it infinitely worse! I did really like the fact that I was always sure I'd got all the lucrin in, but could never tell if my constant congestion was stopping me from absorbing the synarel. When they said it was two squirts of synarel twice a day or lucrin, I jumped right on the lucrin!

BW