Miss K - I am only on the crinone....however i can't help you with that question...just leave them back out to get to room temperature and see what happens..alternatively, you can contact your local pharmacist and ask them...as for the change of body temp killing embryos..well...i dunno..but like you i love hot hot showers no matter what the temp is outside..as for baths and spas etc..i have been told that that is a no no!! i think you should just start popping the panadol for pain relief.