Not sure if this is the right forum for this, but it seems to be the best place I can think of...

Last Friday I skipped my methotrexate.
The one before that I took 10mg instead of the usual 17.5mg
Before that I skipped it completely.
Before that I took 10mg.
Before that I skipped it completely
Before that was the last time I actually took my full dose as prescribed.

I had blood taken on Thursday in preparation for an appointment with my rheumatologist today. I expected my inflammation markers to be sky-high, but everything else to be ok. I expected to get a lecture on not taking my methotrexate and another one for not calling when I was obviously in so much pain from my blood test results.

What I got... Inflammation markers better than they have been in a while and liver enzymes worse than they have been since I started on the mtx. As they were perfect before we started, that's been the final straw for my rheumy. No more mtx.

Current plan... adding 5mg of prednisone per day. I'd actually done this myself two days ago and am finding that I've gone very quickly from the woman who couldn't get off the lounge to being able to cope with Sam solo through bed time last night. I feel fine today, just tired, but you expect that after episodes of severe pain. Increasing my salazopyrin from 2g per day, initially to 2.5g per day if we can do it without my head falling off, and if I'm ok after a month we can go to 3g per day.

And the scary part of this - my rheumy has suggested that going back to IVF is a now or never kind of thing. We have to kick the mtx before it completely trashes my liver, and he really doesn't want to go to the other options until we have closed the door on IVF.

So now I just need to collar DH and get him to sit down and talk to me about whether we go back again or not.

Weird that I'm so freaked out by hearing my rheumy say it when it was what I was thinking anyway...

And I guess that the all-too familiar pain in my chest that I thought was sore joints in my rib cage (because it eased when I took my bra off) is actually an inflamed and very unhappy liver - which coincides with taking the amoxycillin duo forte which is unfortunately the only antibiotic that does anything for my sinus infections but has a long history of pretty severely trashing my liver. Dammit.

BW