PollyA, I have a serum-negative form of rheumatoid arthritis, so you were right on the mark! It isn't causing joint damage but can and will flare up in every single joint of my body - even some of the really fun non-movable joints. I had bad flares after pregnancy which made caring for my new-born a little tricky. In some ways it was good that he was born at 36 weeks weighing just under 2.5kg - I had a very sleepy, light baby who did the newborn eat/sleep thing for a bit longer than most babies. He's now a hyperactive 13kg 18 month old, though. I will certainly keep your suggestions in mind for how to deal with the anemia in a future pregnancy - thank you for that information!

I still haven't spoken to DH. He worked ridiculously long hours on Monday and is quite tired and run down. This morning I did mention the liver problems and the switch from methotrexate back to prednisone - but that was it. When he's in this kind of state, small amounts of information at a time work best. It came up because he wanted to take last night's left overs for lunch today and have lamb shanks for dinner tonight. There's no way my liver in its current state will cope with a meal of lamb shanks (too greasy, I don't much like eating lamb at the best of times!) so I said I'd do the lamb shanks for him and Sam, but would have last night's left overs for dinner instead. He seemed ok with that. I guess there's no particular hurry to make a firm decision yet on what I want to do. I have to give it a little time for the methotrexate to get out of my system before we do anything, anyway.

I won't increase the salazopyrin until my liver feels a bit less congested, and my rheumy wants me to stay on the megafol until I am advised otherwise by FS/OB. I have ridiculously high folate levels from the last check my GP did, but I'll be a good girl and follow instructions. Ironically, in that last check, I also had very high iron levels and currently don't take any supplements containing iron! Already have the calcium/vitamin D supplements going to help my bones cope with the prednisone's calcium depletion...

Rambling... I just wish it was an easier decision to make!

BW