We don't have to fold/unfold often as I walk everywhere, but that's the great thing about living in a smaller town. But yeah I would leave bubs in the car, get the pram out & yourself organised etc otherwise it's a little too hard. I don't really see much benefit in the one hand thing....though having said that I can lift mine open with one hand & one foot on the wheel (I have the Valco runabout), but then I need two hand to ensure it's locked into place - if that makes sense.
In regards to public transport, not that I use it often...but that's what we bought our cheap stroller for, it folds smaller but still not that easy to do so with one hand. I wouldn't choose a heavy pram just for that reason, if you can fold it with one hand but then can't even lift it onto the bus with bubs & a bag of shopping then doesn't seem worth it to me.