TTC & Taking Clomid &/Or Metformin ~ Jan/Feb 2008

[Mel A]

Well i'm back in the game.
AF turned up today, so were back TTC after our M/C. 100mg day 2-6 the DTD every 36hrs day 10-18.

cross fingers we don't have to wait that long...

[DrGirl72]

Hi Everyone, I am CD10 of my first cycle using clomid (took it days 3-7 at 25mg a day). Its been prescribed to try to help with a short luteal phase. I have my first transvaginal uss on tuesday (CD14) which i'm terrified about and had my first accupuncture session yesterday with someone who sepcializes in fertility treatment. Earlier in this thread Hollye9188 said that clomid interferes with opk's. Does anyone know how this works? I use opks as the main way of telling when to do an insemination (my female partner and I are using a known donor) and if they didn't work then not sure how we'd work out the timing. Any thougths greatly appreciaited, thanks

[[M]umma[M]ia]

hey,

yes i have been told by many docs, FS and gynos that clomid can interfere with opk's. Im not to sure why this is but i have always been told while on clomid its a waste of time to do home opk's and to go get the bloodtest done at day 21. This did work for me coz i have done opk's and they never said i was "o". but when i went for my bt, i did "o" and now im 8 weeks pregnant.

Please dont take this as "dont u dare do opk's". Its just wat i have been told and i wanted to share it with you all..

I have a good feeling about Kim.. let us know what happens!!!!

take care all

ps. sorry drgirl, i didnt read ur post propley. Im not too sure how u would work out the actual day for insemination. If you get a positive reading from an opk, the only choice u have is to go with that. I have no idea coz day 21 would be too late for you, unless u have a bt and ur doc can tell you around what day u "o" coz of ur readings or something?? omg im prob not making any sense. hope all goes well

[TwoMums]

Hey DrGirl72, I would say that you need to either a) have a monitored cycle with a trigger injection to pinpoint ovulation or b) inseminate every second day with fresh sperm from days 10-18 if possible...

I would have thought that day CD14 would be cutting it fine if you have a short LP, but i guess if you go in on day 14 and you are fairly close to ovulating you can inseminate then and then 36 hrs later.... but what if you have already ovulated by day 14. i would have thought you would ovulate by day 14 or at least on day 14 if you have a short LP... spose that depends on how long your cycle is..

IMHO...If you are having an ultrasound, that IS pretty much a monitored cycle, ie. Checking for follicle growth etc... and therefore you may as well trigger when you are close to natural ovulation (have a blood test to confirm) with the HCG injection, saves the guess work... It may be ok for hetro couples not to trigger coz they can just keep on having sex with each other until they are sure ovulation has occurred... but it really depends on how many times you want to inseminate, plus how many times your donor wants to donate per cycle....

The reason why Kim and I have monitored cycles with trigger injection is so we can pinpoint exact ovulation because we have an unknown donor and the sperm is cleaned and frozen for IUI.... we need to pinpoint ovulation with frozen sperm because it doesnt last as long as fresh sperm... you guys have the benefit of fresh sperm, but you also want to sort of pinpoint ovulation a little bit i guess because who wants to inseminate every couple of days for a week with a donor...i dont know, you may, but i wouldn't....

Oh and MelA - Bugger, bugger, bugger.... good luck this cycle! We'll be here to egg you on....get it....egg you on!!! LOL

PS... Kim has sore boobs, extremely sore nipples and she felt sick after eating dinner last night (i didn't) and she feel asleep on the couch by 8pm, she had all the same symptoms last time she was pregnant... although those symptoms started around 10dpo last time. Last night she was 8dpo and today is 9dpo and tomorrow she is 10dpo...ok well you get the point...still counting LOL!

[DrGirl72]

Thanks Hollye9188 and TwoMums.
Re OPKs, my understanding is that they detect the LH surge and that clomid block oestrogen therefore increasing fsh. i vaguely know that fsh levels are related to the timing of the LH surge but i cannot work out how the lh surge would be blocked or whatever to stop a +opk. Anyway any more ideas very welcome, otherwise i will ask my dr on tues.

Re insemination timing.... I have a relatively long follicular phase and usually ovulate between CD 17 and CD21, have a 27-30 day cycle with a 9-11 day luteal phase. I don't know (and maybe someone else can tell me) whether having clomid (CD 3-7) is likely to shorten the follicular phase and therefore make ovulation earlier? I make have to chat with our donor re doing more inseminations over a longer time if we are not going to be able to rely on opks. Will also ask dr re trigger shot, thanks twomums for that... Does trigger shot need to come from fs or do general obstetricians prescribe them??? thanks again, girldoc

[TwoMums]

DrGirl72 - Clomid should make your follicle grow faster therefore getting to the size needed to ovulate quicker, but the trigger shot also helps the final maturisation of the egg as well. As far as i know only your FS can give you HCG for the trigger.

[[M]umma[M]ia]

hey

Megan - they are very promising signs because thats how i felt i started getting tired from about 7dpo..but i just assumed i was getting sick or i was just lazy?!? well it turned out i was preggas and now just over 8 weeks..

Gooooooooooooooood LUCK!!!