goodluck everyone for your current cycles and those waiting on EPU/transfers and betas. It is so heartwarmign to see the BFP's inhere at the moment.
I was checking some old threads the other day and out of less than 30 of us that frequented the LTTTC threads over a period of a (May/June 2005) year -18 months or so 24/29 have given birth / others are currently pregnant and a few even pg naturally after IVF babies with no 2. (3 in case of one with twins first). So never give up hope. I waited 15 years for my boys.Unexplained infertility. I never thought it would happen.
Though we only had IVF for 6 months before falling pregnant.
I agree BW - give your DH a hand if need be - your don't want to be b'ding with enlarged ovaries - really it can bruise them besides being shockingly painful.
About no of eggs ... on cycle 2 - I had 19 eggs collected ...17 fertilised normally and we ended up with 5 blasts (on day 6) - but only 2 hatching blasts were suitable to transfer and they others were not suitable to freeze.
Our 1st cycle we had 17 eggs - 13 fertilised - 8 embryos at day 2 , 2 day2 embryos were transferred BFN - when we had FET - they used 5 embryos to get two embryos to transfer - the others failed thawing process BFN.
The remaining embryo also failed thawing process.
Not that I want anyone to say this will happen in very case but just to give you an example of different scenarios. It was probably the lest best embryo from first cycle ... ie they thaw the best embryos first.
On 2nd cycle - I was mentally freaking out with 17 fertilised embryos because we would never discard/donate them... but it worked out ...
Our last two embryos ...now our precious twins.
Looks like we've got bigger things to worry about that potentially huge numbers of embryos...
Today's levels: 13200. Tonight I'm to drop to 75IU of puregon and back for another scan and a blood test tomorrow morning. I'm so sick of the drive to Parramatta!
Apparently my FS is worried. I'm freaking out because the FS is worried.
Trying to keep everything straight that the nurse told me earlier.
If we have some dominant follies, then everything should be ok, but I'm looking at collection, fertilisation and then freezing all embies - no transfer. Looks like they will need to keep the HCG trigger to a fairly low amount if we can go ahead at all. She didn't want to say what would happen if there were no dominant follies, but overall, things are looking pretty grim.
They are really, really worried about OHSS and the way my levels keep shooting up. Thing is, I feel physically fine apart from the pain in my ovaries and the fact that they hurt with every single step that I take. The whole moving around thing isn't big on my priorities right now. Is it possible to feel fine now, but still get OHSS after collection? Or is the fact that I'm feeling fine, but hurting a good sign? Is the pain itself enough of an indicator that there are problems?
I've been through so much to even get to this point, I'm really not coping at all well with the prospect of having ovaries full of eggs, and then to be unable to use them. Being unable to transfer is one thing that's difficult enough, but to be looking at the whole cycle being cancelled now...
BW - I hope it all sorts out for you.I was faced with cancelling my first cycle because they though OHSS too. The ovary pain is normal when you are close to pickup especially if you have lots of follicles.
They skipped the last dose of Puregon, then I was allowed to trigger - with option of a freeze all but because I got under 20 eggs and a blood test showed my E2 levels okay the next day. I was allowed to transfer.
That they are still letting your continue on 75iu Purgeon means they must feel it is okay to continue at this stage ... otherwise if is was grim they would say stop completely.
It is possible initially to feel okay if you are close to OHSS but not if you have it.It can be serious - so at worse better a cancelled cycle than to proceed I was told. Trust your FS and rest too.
ediited to add - yes OHSS can happen after collection ...and it can be serious if you get pregnant as OHSS is worse if you are on the verge anyway.
Keen knows more about OHSS.
Last edited by Baby~amore`; March 29th, 2007 at 05:18 PM.
Thanks, Trish. It's getting information like that that calms me down. I guess it's all fear of the unkown that makes me freak out.
I don't think I'm in any danger of having more than 20 eggs. My left ovary had the most follies -12, there were less on the right, and they aren't expecting all my follies to produce an egg.
It's hard to trust the FS when he's so distant at the moment - everything is going through the nurses at the moment. Even though there were some who I initially didn't like, they all seem to be coming through for me now - very supportive and very willing to answer questions for me, which is good. It helps a little. It doesn't help when they end a phone call with "try not to worry until we see how things go at the scan tomorrow". Yeah, right.
Just a quick question, to do a FET cycle for one to transfer, do they thaw just the one? Still new to all this..
Make that two questions, in your experience and knowledge do the lower grades which have been frozen still have a good chance of blossoming? I know all ours weren't all grade1's
Smudge, I think they would thaw one at a time until they get one that survives the thaw. Maybe? That's just what I imagine and I could be completely wrong.
they thaw one (or 2 in case you are transfering two) at a time and scientist watches to see if they are dividing.They told me it only takes an hour or so to know if the embryo is suitable. If one doesn't make it they take the next in line.
All grades I have heard can blossom into a miracle. I have heard of very poor embryos going the distance and the previous best not from same EPU !
Regarding the grading all fertility centres grade differently and some don't tell you. WFC just told us cells' no.s and that you can't 'really tell' in early stages. Like they can't tell or see DNA structure either.
Usually, the more cells the better - so at day 2 - approx 4 to 8 cells 4 is good to 8 cells is great - after this when cells divide more prolifically after day3 -sometimes slow embryos might only have 2 cells on day 2.
When they defrost - some cells can be lost so a 4 cell might go back to 3 cells ... then starts dividing again.
With blasts I am not so sure but they could see our embryos starting to hatch and in our case the scientist said the last 3 embryos wouldn't freeze well or there was a problem with structure ... not 100 % sure of the wording but part of it starts to divide into baby/sac etc and rest the pre-placenta for implantation. Implantation starts to happen day 6-7 or so.
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